Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 1/20 | 0.52 |
| ▸ | OGA | O60502 | 1/20 | 0.45 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30637430 | 0.90 | SORD (0.47) | SORDOGASLC6A7KDM4EALDH1A1 | |
| SCHEMBL15345159 | 0.83 | SORD (0.52) | SORDOGASLC6A7KDM4EALDH1A1 | |
| SCHEMBL30637363 | 0.81 | SORD (0.45) | SORDOGASLC6A7KDM4EALDH1A1 | |
| SCHEMBL18228454 | 0.80 | SORD (0.55) | SORDOGASLC6A7KDM4EALDH1A1 | |
| SCHEMBL7904079 | 0.80 | SORD (0.55) | SORDOGASLC6A7KDM4EALDH1A1 | |
| SCHEMBL13806030 | 0.80 | SORD (0.55) | SORDOGASLC6A7KDM4EALDH1A1 | |
| SCHEMBL22119525 | 0.80 | OGA (0.44) | OGA | |
| SCHEMBL30600608 | 0.80 | SUV39H2 (0.38) | SORDHSD17B10MAPK1 | |
| SCHEMBL30600618 | 0.80 | OGA (0.48) | OGAHCRTR1HCRTR2 | |
| SCHEMBL22148549 | 0.79 | KMT2A (0.53) | SORDKDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4524136-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | Shanghai Apeiron Therapeutics Company Limited (CN) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023217232-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |
| WO-2023217233-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |
| WO-2023198209-A1 | KIF18A INHIBITOR AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-10-19 | — | — | WO | disclosed |
| CN-116789637-A | Kinesin KIF18A inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2023-09-22 | — | — | CN | disclosed |