Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.37 |
| ▸ | CCR4 | P51679 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | WHR1 | P49842 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SORD | Q00796 | 1/20 | 0.35 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28106523 | 0.82 | ACHE (0.43) | SUV39H2ADRB1ACHE | |
| SCHEMBL26646178 | 0.80 | SORD (0.52) | MAPK1HSD17B10SORD | |
| SCHEMBL3110457 | 0.78 | PIK3CA (0.50) | CYP1A2TSHRMAPK1ACHE | |
| SCHEMBL26684341 | 0.78 | ACHE (0.55) | SUV39H2ACACBCYP1A2CYP3A4HSD17B10 | |
| SCHEMBL22119525 | 0.76 | OGA (0.44) | ACACBTRPV3ADRB1ROCK2CYP3A4 | |
| SCHEMBL30600618 | 0.76 | OGA (0.48) | ACACBWHR1 | |
| SCHEMBL29367680 | 0.74 | ADRB1 (0.47) | ACACBTRPV3ADRB1SORDKIF18A | |
| SCHEMBL20746494 | 0.73 | TRPV3 (0.42) | ACACBTRPV3ADRB1ROCK2SORD | |
| SCHEMBL30079990 | 0.73 | CYP3A4 (0.56) | CYP1A2CYP3A4TSHRHSD17B10 | |
| SCHEMBL31346934 | 0.72 | RBP4 (0.45) | ACACBROCK2CYP1A2CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217232-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |