Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.49 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21179225 | 1.00 | MTNR1A (0.49) | MTNR1AMTNR1BPLA2G10FFAR1MAOA | |
| SCHEMBL1743680 | 1.00 | MTNR1A (0.49) | MTNR1AMTNR1BPLA2G10FFAR1MAOA | |
| SCHEMBL25711918 | 0.81 | ATM (0.50) | MTNR1AMTNR1BCYP3A4MAPTALDH1A1 | |
| SCHEMBL19014798 | 0.81 | ATM (0.50) | MTNR1AMTNR1BCYP3A4MAPTALDH1A1 | |
| SCHEMBL31467022 | 0.81 | CTRB1 (0.52) | — | |
| SCHEMBL26648108 | 0.79 | MTNR1A (0.50) | MTNR1AMTNR1BPLA2G10FFAR1MAOA | |
| SCHEMBL2951869 | 0.78 | MTNR1A (0.51) | MTNR1AMTNR1BPLA2G10FFAR1MAOA | |
| SCHEMBL30857646 | 0.77 | MTNR1A (0.38) | MTNR1AMTNR1BPLA2G10FFAR1NPC1 | |
| SCHEMBL2950983 | 0.77 | MTNR1A (0.51) | MTNR1AMTNR1BPLA2G10FFAR1MAOA | |
| SCHEMBL4901823 | 0.76 | MTNR1A (0.50) | MTNR1AMTNR1BPLA2G10FFAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220425-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |