Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.50 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | FCER2 | P06734 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14067148 | 0.82 | CTRB1 (0.50) | MTNR1AMTNR1BPLA2G10PLA2G2AATM | |
| SCHEMBL3590845 | 0.81 | MTNR1A (0.49) | MTNR1AMTNR1BPLA2G10PLA2G2AL3MBTL1 | |
| SCHEMBL553506 | 0.81 | MTNR1A (0.49) | MTNR1AMTNR1BPLA2G10PLA2G2AL3MBTL1 | |
| SCHEMBL8212610 | 0.80 | PLA2G10 (0.50) | MTNR1AMTNR1BPLA2G10PLA2G2AL3MBTL1 | |
| SCHEMBL22409485 | 0.79 | MTNR1A (0.50) | MTNR1AMTNR1BPLA2G10PLA2G2AL3MBTL1 | |
| SCHEMBL21179176 | 0.79 | MTNR1A (0.50) | MTNR1AMTNR1BPLA2G10PLA2G2AL3MBTL1 | |
| SCHEMBL1540158 | 0.79 | MAOA (0.50) | MTNR1AMTNR1BPLA2G10ATMSLC6A3 | |
| SCHEMBL4905285 | 0.79 | MAOA (0.50) | MTNR1AMTNR1BPLA2G10ATMSLC6A3 | |
| SCHEMBL1540157 | 0.79 | MTNR1A (0.49) | MTNR1AMTNR1BPLA2G10PLA2G2AATM | |
| SCHEMBL2950983 | 0.78 | MTNR1A (0.51) | MTNR1AMTNR1BPLA2G10PLA2G2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221132-A1 | Multi-Functional Small Molecules as Anti-Proliferative Agents | CURIS, INC. | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221132-A1 | Multi-Functional Small Molecules as Anti-Proliferative Agents | HDAC1, HDAC6, HDAC5 | MTNR1A 3457/4885MTNR1B 3760/4885PLA2G10 4296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.