Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 16/20 | 0.47 |
| ▸ | GIPR | P48546 | 12/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | GLP1R | P43220 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665082 | 0.88 | GCGR (0.46) | GCGRGIPRPPARDPPARGPPARA | |
| SCHEMBL2665121 | 0.85 | GCGR (0.51) | GCGRGIPRPPARDPPARGPPARA | |
| SCHEMBL2665120 | 0.85 | GCGR (0.49) | GCGRGIPRPPARDGLP1R | |
| SCHEMBL9071500 | 0.85 | GCGR (0.47) | GCGRGIPR | |
| SCHEMBL6910310 | 0.81 | GCGR (0.53) | GCGRGIPRPPARDPPARGPPARA | |
| SCHEMBL6910175 | 0.81 | GCGR (0.53) | GCGRGIPRPPARDPPARGPPARA | |
| SCHEMBL2665036 | 0.81 | GCGR (0.53) | GCGRGIPRPPARDPPARGPPARA | |
| SCHEMBL6910313 | 0.81 | GCGR (0.53) | GCGRGIPRPPARDPPARGPPARA | |
| SCHEMBL2665050 | 0.78 | GCGR (0.55) | GCGRGIPRPPARDPPARGPPARA | |
| SCHEMBL6915810 | 0.78 | GCGR (0.47) | GCGRGIPRPPARDPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |