Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 10/20 | 0.55 |
| ▸ | GIPR | P48546 | 10/20 | 0.55 |
| ▸ | GLP1R | P43220 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.34 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665083 | 0.87 | GCGR (0.44) | GCGRGIPRPPARDTAOK1TAOK3 | |
| SCHEMBL2664963 | 0.84 | GCGR (0.41) | GCGRGIPRGLP1RPPARD | |
| SCHEMBL2664962 | 0.84 | GCGR (0.40) | GCGRGIPRPPARD | |
| SCHEMBL2665047 | 0.84 | GCGR (0.45) | GCGRGIPRPPARGPPARA | |
| SCHEMBL2665220 | 0.82 | GCGR (0.46) | GCGRGIPRPPARDTAOK1TAOK3 | |
| SCHEMBL9071500 | 0.81 | GCGR (0.47) | GCGRGIPRTAOK1TAOK3 | |
| SCHEMBL6910313 | 0.81 | GCGR (0.53) | GCGRGIPRGLP1RPPARDTAOK1 | |
| SCHEMBL2665036 | 0.81 | GCGR (0.53) | GCGRGIPRGLP1RPPARDTAOK1 | |
| SCHEMBL6910175 | 0.81 | GCGR (0.53) | GCGRGIPRGLP1RPPARDTAOK1 | |
| SCHEMBL6910310 | 0.81 | GCGR (0.53) | GCGRGIPRGLP1RPPARDTAOK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |