Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29226156 | 0.88 | EP300 (0.41) | CCR2PLA2G2AEP300EPHX2GRIK1 | |
| SCHEMBL27823589 | 0.83 | EGLN1 (0.32) | EGLN1 | |
| SCHEMBL973819 | 0.80 | ALDH1A1 (0.33) | EGLN1ALDH1A1 | |
| SCHEMBL9302994 | 0.80 | TET2 (0.32) | EGLN1 | |
| SCHEMBL973821 | 0.80 | ALDH1A1 (0.33) | EGLN1ALDH1A1 | |
| SCHEMBL29274382 | 0.79 | — | — | |
| SCHEMBL28690185 | 0.78 | CCR2 (0.33) | CCR2GRIK1GRIK2ALDH1A1 | |
| SCHEMBL383606 | 0.78 | HDAC8 (0.36) | CCR2GRIK1GRIK2ALDH1A1 | |
| SCHEMBL8847260 | 0.77 | GRIK1 (0.31) | GRIK1GRIK2 | |
| SCHEMBL8847263 | 0.77 | GRIK1 (0.31) | GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105663033-B | Intratumor injection temperature sensitive polymer gel nano-composition in situ and application | 华中科技大学 | 2019-04-19 | — | — | CN | claimed |
| US-12001228-B2 | Thermal diode and thermal switch for bi-directional heat transfer in building envelopes | ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) | 2024-06-04 | — | — | US | disclosed |
| US-11819823-B2 | Super-adsorbing porous thermo-responsive desiccants | ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) | 2023-11-21 | — | — | US | disclosed |
| CN-107137724-B | Material for constructing temperature-responsive aggregate in cell and preparation method and application thereof | 国家纳米科学中心 | 2020-11-10 | — | — | CN | disclosed |
| CN-107397959-B | Preparation method and application of nano antagonist with ultrastructure on surface | 国家纳米科学中心 | 2020-10-16 | — | — | CN | disclosed |
| CN-105663033-B | Intratumor injection temperature sensitive polymer gel nano-composition in situ and application | 华中科技大学 | 2019-04-19 | — | — | CN | disclosed |