SCHEMBL383606

SCHEMBL383606

CCCC=C(C)C(=O)NO

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 2/20 0.36
HDAC6 Q9UBN7 2/20 0.36
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
KDM4E B2RXH2 1/20 0.33
CA2 P00918 1/20 0.33
PTGS1 P23219 1/20 0.33
MMP12 P39900 1/20 0.33
CCR2 P41597 1/20 0.33
GRIK1 P39086 1/20 0.32
GRIK2 Q13002 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC9 Q9UKV0 1/20 0.32
HDAC5 Q9UQL6 1/20 0.32
HSP90AA1 P07900 1/20 0.31
ALDH1A1 P00352 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278339 0.88 KDM4E (0.38) HDAC1KDM4ECA2PTGS1MMP12
SCHEMBL20504550 0.88 KDM4E (0.38) HDAC1KDM4ECA2PTGS1MMP12
SCHEMBL27905560 0.87 CCR2 (0.40) HDAC8HDAC6HDAC3HDAC1HDAC2
SCHEMBL28690185 0.82 CCR2 (0.33) CCR2GRIK1GRIK2ALDH1A1
SCHEMBL2350820 0.81
SCHEMBL340695 0.80 CTSD (0.38) KDM4ECA2CCR2GRIK1GRIK2
SCHEMBL3286598 0.78 CCR2 (0.31) KDM4ECCR2GRIK1GRIK2
SCHEMBL26650993 0.78 CCR2 (0.34) CCR2GRIK1GRIK2ALDH1A1
Hydrochloric Acid SCHEMBL8900383 0.78 CTSD (0.37) KDM4ECCR2GRIK1GRIK2ALDH1A1
SCHEMBL565768 0.77 KDM7A (0.32) CCR2GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113908289-B Antitumor multi-element drug-carrying system with precisely regulated and controlled drug proportion and preparation method thereof 北京化工大学 2023-07-25 CN claimed
CN-114621393-A Copolymer of N- (2-hydroxy) propyl methacrylamide and N-methacryloyl glycyl glycine and application thereof 华侨大学 2022-06-14 CN claimed
CN-113908289-A Anti-tumor multi-element drug loading system with accurately regulated drug proportion and preparation method thereof 北京化工大学 2022-01-11 CN claimed
CN-112604003-B Anti-tumor composition based on nano-silver material and application thereof 湖南航天天麓新材料检测有限责任公司 2021-08-20 CN claimed
CN-110613734-B Polymer/silver activity bonding substance for inhibiting proliferation of activated macrophages, and preparation and application thereof 中南大学 2020-06-16 CN claimed
CN-110613734-A Polymer/silver activity bonding substance for inhibiting proliferation of activated macrophages, and preparation and application thereof 中南大学 2019-12-27 CN claimed
CN-103936945-B Efficient anti-tumor targeting drug carrier and preparation method thereof 中国科学院化学研究所 2017-02-08 CN claimed
CN-102803228-B The unstable triggers unit of acid KTB TUMORFORSCHUNGSGESELLSCHAFT MBH (DE) 2015-11-25 CN claimed
EP-1763364-A2 METHODS AND COMPOSITIONS COMPRISING SUPRAMOLECULAR CONSTRUCTS AC Immune S.A. (CH) 2007-03-21 EP claimed
WO-2005081872-A2 METHODS AND COMPOSITIONS COMPRISING SUPRAMOLECULAR CONSTRUCTS AC IMMUNE SA (CH) 2005-09-09 WO claimed
WO-1992019288-A1 CATHETER HAVING A COATING ON THE EXPOSED SURFACE THEREOF PHARMA-PLAST INTERNATIONAL A/S (DK) 1992-11-12 WO claimed
EP-2632434-B1 LIPOSOME-BASED CONSTRUCT COMPRISING A PEPTIDE MODIFIED THROUGH HYDROPHOBIC MOIETIES AC IMMUNE SA (CH) 2025-08-20 EP disclosed
US-20240270829-A1 Vaccine Therapy AC IMMUNE SA (CH) 2024-08-15 US disclosed
CN-113908289-B Antitumor multi-element drug-carrying system with precisely regulated and controlled drug proportion and preparation method thereof 北京化工大学 2023-07-25 CN disclosed
CN-113908289-B Antitumor multi-element drug-carrying system with precisely regulated and controlled drug proportion and preparation method thereof 北京化工大学 2023-07-25 CN disclosed
WO-2007068411-A2 THERAPEUTIC VACCINE AC IMMUNE S.A. (CH) 2007-06-21 WO disclosed
EP-1763364-A2 METHODS AND COMPOSITIONS COMPRISING SUPRAMOLECULAR CONSTRUCTS AC Immune S.A. (CH) 2007-03-21 EP disclosed
US-20060233758-A1 Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers AC IMMUNE SA (CH) 2006-10-19 US disclosed
US-20050255561-A1 Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers AC IMMUNE SA (CH) 2005-11-17 US disclosed
WO-2005081872-A2 METHODS AND COMPOSITIONS COMPRISING SUPRAMOLECULAR CONSTRUCTS AC IMMUNE SA (CH) 2005-09-09 WO disclosed