Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GCGR | P47871 | 11/20 | 0.41 |
| ▸ | GIPR | P48546 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ADCY6 | O43306 | 3/20 | 0.40 |
| ▸ | ADCY3 | O60266 | 3/20 | 0.40 |
| ▸ | ADCY9 | O60503 | 3/20 | 0.40 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.40 |
| ▸ | ADCY8 | P40145 | 3/20 | 0.40 |
| ▸ | ADCY7 | P51828 | 3/20 | 0.40 |
| ▸ | ADCY2 | Q08462 | 3/20 | 0.40 |
| ▸ | ADCY1 | Q08828 | 3/20 | 0.40 |
| ▸ | ADCY4 | Q8NFM4 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665223 | 0.87 | GCGR (0.43) | KMT2AGCGRGIPRNPC1RAB9A | |
| SCHEMBL2665224 | 0.85 | GCGR (0.43) | GCGRGIPRNPC1RAB9AADCY6 | |
| SCHEMBL2655953 | 0.85 | GCGR (0.52) | GCGRGIPR | |
| SCHEMBL2655948 | 0.85 | GCGR (0.52) | GCGRGIPR | |
| SCHEMBL2665228 | 0.85 | GCGR (0.44) | KMT2AGCGRGIPRNR1H4EPHX2 | |
| SCHEMBL2665164 | 0.85 | GCGR (0.47) | GCGRGIPREPHX2ALDH1A1 | |
| SCHEMBL2665084 | 0.85 | GCGR (0.42) | KMT2AGCGRGIPRRAB9ASMN1; SMN2 | |
| SCHEMBL2665226 | 0.83 | FABP4 (0.43) | GCGRGIPRNPC1RAB9AALDH1A1 | |
| SCHEMBL2665225 | 0.83 | GCGR (0.52) | GCGRGIPR | |
| SCHEMBL2665091 | 0.83 | GCGR (0.42) | GCGRGIPRNR1H4EPHX2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |