Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26654074 | 1.00 | CA2 (0.39) | CA2CA9CA12CA1CA3 | |
| SCHEMBL30658029 | 0.88 | CA2 (0.39) | CA2CA9CA12CA1CA3 | |
| SCHEMBL26653977 | 0.84 | CA2 (0.40) | CA2CA9CA12CA1CA3 | |
| SCHEMBL26653979 | 0.84 | CA2 (0.40) | CA2CA9CA12CA1CA3 | |
| SCHEMBL13062397 | 0.76 | CA2 (0.47) | CA2CA9CA12CA1CA3 | |
| SCHEMBL30657998 | 0.75 | CA2 (0.39) | CA2CA9CA12CA1CA3 | |
| SCHEMBL3727950 | 0.72 | CA2 (0.69) | CA2CA9CA12CA1CA3 | |
| SCHEMBL26683331 | 0.71 | CA12 (0.40) | CA2CA9CA12CA1CA3 | |
| SCHEMBL26684381 | 0.71 | CA12 (0.40) | CA2CA9CA12CA1CA3 | |
| SCHEMBL31605659 | 0.70 | LGALS3 (0.35) | CA2CA9CA12CA1CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220134-A1 | PYRAZINE DERIVATIVES AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |