Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 6/20 | 0.35 |
| ▸ | IDH2 | P48735 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | USP1 | O94782 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL695186 | 0.80 | NPC1 (0.50) | NPC1RAB9AMAPTNPSR1HTT | |
| SCHEMBL28869852 | 0.78 | NPC1 (0.48) | NPC1RAB9AMAPTNPSR1HTT | |
| SCHEMBL2692140 | 0.72 | NPC1 (0.46) | NPC1RAB9AMAPTNPSR1HTT | |
| SCHEMBL4608788 | 0.72 | NPC1 (0.45) | NPC1RAB9AMAPTNPSR1HTT | |
| SCHEMBL1094013 | 0.72 | NPC1 (0.63) | NPC1RAB9AMAPTNPSR1HTT | |
| SCHEMBL30276673 | 0.71 | POLB (0.46) | NPC1RAB9AMAPTNPSR1HTT | |
| SCHEMBL30999699 | 0.70 | NPC1 (0.54) | NPC1RAB9AMAPTNPSR1HTT | |
| SCHEMBL21023945 | 0.70 | NPC1 (0.54) | NPC1RAB9AMAPTNPSR1HTT | |
| SCHEMBL24484298 | 0.69 | NPC1 (0.52) | NPC1RAB9AMAPTNPSR1HTT | |
| SCHEMBL15299351 | 0.69 | NPC1 (0.52) | NPC1RAB9AMAPTNPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784661-B1 | NOVEL HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES | BAYER AG (DE) | 2023-11-22 | — | — | EP | claimed |
| CN-112204021-A | Novel heteroaryltriazole and heteroaryltetrazole compounds as pesticides | 拜耳公司 | 2021-01-08 | — | — | CN | claimed |
| CN-112204021-A | Novel heteroaryltriazole and heteroaryltetrazole compounds as pesticides | 拜耳公司 | 2021-01-08 | — | — | CN | disclosed |