Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CBX7 | O95931 | 1/20 | 0.37 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31457804 | 1.00 | L3MBTL1 (0.40) | L3MBTL1HTTUSP2DRD2HTR2A | |
| SCHEMBL30665851 | 0.88 | TSHR (0.43) | L3MBTL1DRD2HTR2AMCHR1TSHR | |
| SCHEMBL26654819 | 0.88 | TSHR (0.43) | L3MBTL1DRD2HTR2AMCHR1TSHR | |
| SCHEMBL30659715 | 0.84 | L3MBTL1 (0.37) | L3MBTL1HTTDRD2HTR2AMCHR1 | |
| SCHEMBL26654477 | 0.84 | L3MBTL1 (0.37) | L3MBTL1HTTDRD2HTR2AMCHR1 | |
| SCHEMBL26654630 | 0.83 | NOS3 (0.44) | L3MBTL1DRD2HTR2AMCHR1TSHR | |
| SCHEMBL30659620 | 0.83 | NOS3 (0.44) | L3MBTL1DRD2HTR2AMCHR1TSHR | |
| SCHEMBL30659587 | 0.83 | HTR1A (0.45) | L3MBTL1DRD2HTR2AMCHR1TSHR | |
| SCHEMBL26654576 | 0.83 | HTR1A (0.45) | L3MBTL1DRD2HTR2AMCHR1TSHR | |
| SCHEMBL30659611 | 0.82 | HTR2A (0.47) | DRD2HTR2AMCHR1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069725-A | Imidazopyridazine substituted benzene ring derivative, preparation method, pharmaceutical composition and application | 上海赛默罗生物科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| WO-2023216753-A1 | IMIDAZOPYRIDAZINE SUBSTITUTED BENZENE RING DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | 上海赛默罗生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |