SCHEMBL26655657

SCHEMBL26655657

CCCCCCCCCCOC1OCc2cnc(C)c(O)c21

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
P2RX3 P56373 1/20 0.35
KMT2A Q03164 1/20 0.35
GBA1 P04062 2/20 0.34
NR5A1 Q13285 1/20 0.33
ESR1 P03372 1/20 0.31
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21215169 1.00 KDM4E (0.35) KDM4EMEN1CYP1A2CYP2D6CYP2C19
SCHEMBL13995529 0.66 KDM4E (0.39) KDM4EMEN1CYP1A2CYP2D6CYP2C19
SCHEMBL19969259 0.62 LMNA (0.49) KDM4EMEN1KMT2ANR5A1ESR1
SCHEMBL14141549 0.60 NR5A1 (0.46) NR5A1ESR1
SCHEMBL19969290 0.60 LMNA (0.50) KDM4EMEN1KMT2ANR5A1ESR1
SCHEMBL24319905 0.58 KDM4E (0.44) KDM4EMEN1CYP1A2CYP2D6CYP2C19
SCHEMBL28662237 0.58 GBA1 (0.39) MEN1KMT2AGBA1NR5A1ALDH1A1
SCHEMBL19127440 0.57 NR5A1 (0.42) MEN1KMT2ANR5A1ESR1ALDH1A1
SCHEMBL2321510 0.57 ALDH1A1 (0.53) GBA1ALDH1A1TDP1
SCHEMBL1706788 0.57 ALDH1A1 (0.53) GBA1ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3743410-B1 USE OF PYRIDOXAL ACETAL SALTS AS WATER-TRIGGERED PROFRAGRANCES FLORIDA GULF COAST UNIV BOARD OF TRUSTEES (US) 2023-10-25 EP disclosed