Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13227810 | 0.79 | NOTUM (0.50) | PRCPNOTUMROCK1DRD2DRD4 | |
| SCHEMBL16685269 | 0.75 | NOTUM (0.50) | NOTUMROCK1OPRM1HTR1ADRD2 | |
| SCHEMBL28389409 | 0.74 | ALDH1A1 (0.36) | PRCPNOTUMOPRM1OPRD1SIGMAR1 | |
| SCHEMBL28385715 | 0.74 | NOTUM (0.49) | PRCPNOTUMROCK1OPRM1DRD2 | |
| SCHEMBL9501335 | 0.73 | CACNA1I (0.54) | NOTUMROCK1DRD2DRD4ALOX12 | |
| SCHEMBL9636500 | 0.72 | CRHBP (0.43) | PRCPNOTUMOPRM1OPRD1SIGMAR1 | |
| SCHEMBL7695554 | 0.71 | SIRT2 (0.51) | NOTUMALOX12MAPT | |
| SCHEMBL2571298 | 0.70 | ADRA1D (0.42) | PRCPOPRM1OPRD1ADRA1DADRA1A | |
| SCHEMBL19949789 | 0.70 | ADRA1D (0.42) | PRCPOPRD1HTR1AADRA1DADRA1A | |
| SCHEMBL7862113 | 0.70 | SMN1; SMN2 (0.35) | PRCPNOTUMALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004082565-A2 | ASYMMETRIC CYCLIZATION IN THE PRESENCE OF SUBSTITUTED PSEUDOPHEDRINES | H. LUNDBECK A/S (DK) | 2004-09-30 | — | — | WO | disclosed |