Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.70 |
| ▸ | CTSG | P08311 | 1/20 | 0.70 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.70 |
| ▸ | CMA1 | P23946 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Betamipron SCHEMBL4498475 | 1.00 | PRSS1 (0.70) | PRSS1CTSGCTRB1CMA1GAA | |
| SCHEMBL9717434 | 0.91 | MAPK1 (0.71) | PRSS1CTSGCTRB1CMA1GAA | |
| SCHEMBL2033165 | 0.88 | MAPK1 (0.73) | PRSS1CTSGCTRB1CMA1GAA | |
| SCHEMBL9717417 | 0.88 | ITGB3 (0.65) | PRSS1CTSGCTRB1CMA1GAA | |
| SCHEMBL9829615 | 0.87 | GAA (0.57) | PRSS1CTSGCTRB1CMA1GAA | |
| SCHEMBL3192014 | 0.87 | LMNA (0.77) | PRSS1CTSGCTRB1CMA1GAA | |
| Betamipron SCHEMBL28084518 | 0.87 | NPC1 (0.73) | PRSS1CTSGCTRB1CMA1SMN1; SMN2 | |
| SCHEMBL950223 | 0.86 | MAPK1 (0.83) | PRSS1CTSGCTRB1CMA1GAA | |
| SCHEMBL2324530 | 0.86 | PRSS1 (0.64) | PRSS1CTSGCTRB1CMA1GAA | |
| SCHEMBL5592824 | 0.86 | PRSS1 (0.68) | PRSS1CTSGCTRB1CMA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1896 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12544359-B2 | 1-aminosulfonyl-2-carboxypyrrole derivatives as metallo-beta-lactamase inhibitors | Infex Therapeutics Limited (GB) | 2026-02-10 | — | — | US | claimed |
| WO-2025264604-A1 | SKIN CARE COMPOSITION AND METHOD OF USING THE SAME | THE PROCTER & GAMBLE COMPANY (US) | 2025-12-26 | — | — | WO | claimed |
| US-20250381110-A1 | SKIN CARE COMPOSITION AND METHOD OF USING THE SAME | PROCTER & GAMBLE (US) | 2025-12-18 | — | — | US | claimed |
| CN-119100967-A | 1-Aminosulfonyl-2-carboxypyrrole derivatives as metallo-beta-lactamase inhibitors | 英菲克斯治疗有限公司 | 2024-12-10 | — | — | CN | claimed |
| CN-114728902-B | 1-Aminosulfonyl-2-carboxypyrrole derivatives as metallo-beta-lactamase inhibitors | 英菲克斯治疗有限公司 | 2024-09-13 | — | — | CN | claimed |
| US-20240216410-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER THERAPY-INDUCED NEUTROPENIC FEVER AND/OR GVHD | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-07-04 | — | — | US | claimed |
| WO-2024123562-A2 | PEPTIDE INHIBITORS OF BETA-LACTAMASE | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2024-06-13 | — | — | WO | claimed |
| EP-4314255-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER THERAPY-INDUCED NEUTROPENIC FEVER AND/OR GVHD | Board of Regents, The University of Texas System (US) | 2024-02-07 | — | — | EP | claimed |
| US-20230414584-A1 | ADMINISTRATION OF ANTIBIOTIC COMPOUNDS FOR THE TREATMENT OF STREPTOCOCCAL INFECTIONS FOR THE TREATMENT OF PSORIASIS | CENTRE FOR DIGESTIVE DISEASES (AU) | 2023-12-28 | — | — | US | claimed |
| CN-115463128-B | Panipenem and betamilone compound combination drug for injection and preparation method thereof | 深圳太太药业有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-1036832-C | Composition containing a penem or carbapenem artibiotic and the use of the same | SANKYO CO (JP) | 1997-12-31 | — | — | CN | claimed |
| US-5044091-A | Frozen first and second liquid freeze dried together | SANKYO COMPANY, LIMITED (JP) | 1991-09-03 | — | — | US | claimed |
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | claimed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | claimed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | claimed |
| CN-86107574-A | Compositions containing penem or carbapenem antibiotics and their use | — | 1987-05-20 | — | — | CN | claimed |
| EP-0029284-B1 | METHOD FOR THE ELECTROPHORETIC SEPARATION OF PROTEINS, A BUFFER SOLUTION AND BUFFER COMPOSITIONS THEREFOR | GELMAN SCIENCES, INC. (US) | 1984-02-15 | — | — | EP | claimed |
| US-4292162-A | A SOLUTION OF TRIS BUFFER, HIPPURIC ACID, AND A WATER-SOLUBLE HIPPURATE | GELMAN SCIENCES, INC. (US) | 1981-09-29 | — | — | US | claimed |
| US-4292154-A | USING A UREA-, AN AMIDE-, OR AMINOCARBOAMIDE-CONTAINING CARBOXYLIC ACID AND THE CORRESPONDING ACID SALT | GELMAN SCIENCES, INC. (US) | 1981-09-29 | — | — | US | claimed |
| EP-0029284-A1 | Method for the electrophoretic separation of proteins, a buffer solution and buffer compositions therefor | GELMAN SCIENCES, INC. (US) | 1981-05-27 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12544359-B2 | 1-aminosulfonyl-2-carboxypyrrole derivatives as metallo-beta-lactamase inhibitors | CBR1, CBR3, SRR | PRSS1 709/4885CTSG 1926/4885CTRB1 148/4885 |
| US-20250381110-A1 | SKIN CARE COMPOSITION AND METHOD OF USING THE SAME | SQSTM1, BECN1, CUTA | PRSS1 4138/4885CTSG 213/4885CTRB1 1810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.