Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 15/20 | 0.43 |
| ▸ | GIPR | P48546 | 15/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665810 | 0.84 | GCGR (0.55) | GCGRGIPR | |
| SCHEMBL9071166 | 0.82 | GCGR (0.44) | GCGRGIPR | |
| SCHEMBL2665930 | 0.77 | CTSL (0.39) | GCGRGIPRMEN1KMT2AGSTO1 | |
| SCHEMBL9071163 | 0.75 | GCGR (0.61) | GCGRGIPR | |
| SCHEMBL2665768 | 0.73 | GCGR (0.62) | GCGRGIPR | |
| SCHEMBL3451487 | 0.73 | KMT2A (0.54) | MEN1KMT2ANPSR1GSTO1L3MBTL1 | |
| SCHEMBL3912223 | 0.72 | PPARD (0.57) | MEN1KMT2ANPSR1 | |
| SCHEMBL3918017 | 0.72 | FFAR1 (0.57) | — | |
| SCHEMBL2665815 | 0.72 | GCGR (0.57) | GCGRGIPR | |
| SCHEMBL2665971 | 0.72 | GCGR (0.54) | GCGRGIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004002480-A1 | NOVEL GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |