Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.60 |
| ▸ | DRD4 | P21917 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657107 | 0.82 | S1PR1 (0.66) | NPC1RAB9ASMN1; SMN2HPGDKMT2A | |
| SCHEMBL9071165 | 0.82 | HDAC8 (0.58) | NPC1RAB9ASMN1; SMN2HDAC1KMT2A | |
| SCHEMBL11424416 | 0.81 | NPC1 (0.93) | NPC1RAB9ASMN1; SMN2HPGDKMT2A | |
| Trifluoroacetic Acid SCHEMBL950311 | 0.79 | LTA4H (0.61) | HDAC1DRD4KMT2AHDAC3HDAC4 | |
| SCHEMBL2651560 | 0.78 | S1PR1 (0.62) | NPC1RAB9ASMN1; SMN2HPGDKMT2A | |
| SCHEMBL1578277 | 0.78 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2HPGDKMT2A | |
| SCHEMBL2665739 | 0.78 | ALDH1A1 (0.57) | SMN1; SMN2HPGDKMT2AMEN1HDAC8 | |
| Trifluoroacetic Acid SCHEMBL949936 | 0.78 | LTA4H (0.63) | HDAC1DRD4KMT2AHDAC3HDAC4 | |
| SCHEMBL9072937 | 0.77 | CA1 (0.52) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL28929666 | 0.77 | CA1 (0.67) | NPC1RAB9ASMN1; SMN2HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004002480-A1 | NOVEL GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |