Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | GCK | P35557 | 7/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071474 | 0.88 | GCK (0.53) | PARP10GCKRARARARBRARG | |
| SCHEMBL14017929 | 0.84 | PARP10 (0.47) | PARP10GCKRARARARBRARG | |
| SCHEMBL9071440 | 0.81 | PARP10 (0.50) | PARP10GCKPLAUF2PLG | |
| SCHEMBL9071442 | 0.78 | PARP10 (0.47) | PARP10GCKRARARARBRARG | |
| SCHEMBL14018037 | 0.78 | PARP10 (0.47) | PARP10GCKRARARARBRARG | |
| SCHEMBL14018622 | 0.77 | PARP10 (0.56) | PARP10GCKIRAK4ACACBACACA | |
| SCHEMBL9071441 | 0.77 | PARP10 (0.53) | PARP10PLAUF2PLGPLAT | |
| SCHEMBL14017899 | 0.77 | PARP10 (0.53) | PARP10GCKPLAUF2PLG | |
| SCHEMBL30151899 | 0.76 | PARP10 (0.61) | PARP10TSHRKMT2AALDH1A1 | |
| SCHEMBL14091195 | 0.76 | PARP10 (0.45) | PARP10GCKRARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003015774-A1 | COMPOUNDS EFFECTING GLUCOKINASE | ASTRAZENECA AB (SE) | 2003-02-27 | — | — | WO | disclosed |