Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | GCK | P35557 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821296 | 0.88 | CA12 (0.42) | PARP10ALDH1A1NPC1POLBMAPT | |
| SCHEMBL9071474 | 0.81 | GCK (0.53) | PARP10PLAUGCKKMT2AF2 | |
| SCHEMBL9071440 | 0.79 | PARP10 (0.50) | PARP10ALDH1A1SMN1; SMN2PLAUGCK | |
| SCHEMBL2666400 | 0.78 | PARP10 (0.49) | PARP10ALDH1A1PLAUGCKKMT2A | |
| SCHEMBL5228091 | 0.78 | ADRB2 (0.40) | ALDH1A1ADRB2ADRB1ADRB3NPC1 | |
| SCHEMBL14017929 | 0.77 | PARP10 (0.47) | PARP10PLAUGCKKMT2AF2 | |
| SCHEMBL14018037 | 0.77 | PARP10 (0.47) | PARP10ALDH1A1PLAUGCKKMT2A | |
| SCHEMBL14018622 | 0.76 | PARP10 (0.56) | PARP10GCKIRAK4 | |
| SCHEMBL9071441 | 0.76 | PARP10 (0.53) | PARP10ALDH1A1PLAUKMT2AF2 | |
| SCHEMBL14017899 | 0.76 | PARP10 (0.53) | PARP10ALDH1A1PLAUGCKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003015774-A1 | COMPOUNDS EFFECTING GLUCOKINASE | ASTRAZENECA AB (SE) | 2003-02-27 | — | — | WO | disclosed |