Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | YAP1 | P46937 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26602811 | 0.86 | CA12 (0.43) | AKR1C3AKR1C2MAPK1MAPTXBP1 | |
| SCHEMBL26665556 | 0.81 | AKR1C3 (0.40) | AKR1C3AKR1C2DHODH | |
| SCHEMBL26665331 | 0.75 | LIPE (0.41) | AKR1C3AKR1C2MAPK1MAPTNPSR1 | |
| SCHEMBL26665296 | 0.75 | MAPT (0.43) | AKR1C3AKR1C2MAPK1MAPTXBP1 | |
| SCHEMBL29074750 | 0.75 | ALDH1A1 (0.50) | AKR1C3AKR1C2MAPK1MAPTXBP1 | |
| SCHEMBL20779892 | 0.74 | TEAD1 (0.62) | AKR1C3AKR1C2MAPK1MAPTTEAD1 | |
| SCHEMBL26603003 | 0.74 | TEAD1 (0.65) | AKR1C3AKR1C2MAPK1TEAD1SMN1; SMN2 | |
| SCHEMBL25431454 | 0.73 | TP53 (0.46) | AKR1C3MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL21053182 | 0.73 | NOTUM (0.58) | AKR1C3AKR1C2MAPTXBP1NPSR1 | |
| SCHEMBL25042639 | 0.71 | SMN1; SMN2 (0.51) | AKR1C3MAPTXBP1NPSR1TEAD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023204822-A1 | PHENYL PHOSPHINE OXIDE COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |