Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20856563 | 0.80 | LMNA (0.38) | HTTLMNATP53ADRB2MAPT | |
| SCHEMBL19976890 | 0.79 | LMNA (0.39) | HTTLMNATP53MAPTGAA | |
| SCHEMBL28841644 | 0.77 | LMNA (0.40) | HTTLMNATP53LPAR1MAPT | |
| SCHEMBL27523153 | 0.77 | LMNA (0.40) | HTTLMNATP53LPAR1GAA | |
| SCHEMBL16040951 | 0.77 | GAA (0.44) | HTTLMNATP53LPAR1MAPT | |
| SCHEMBL19042153 | 0.77 | LPAR1 (0.41) | HTTLMNATP53LPAR1MAPT | |
| SCHEMBL12197660 | 0.73 | GABRA1 (0.52) | HTTLMNATP53ADRB2MAPT | |
| SCHEMBL6821181 | 0.72 | GAA (0.59) | LMNAMAPTGAARAPGEF4ALDH1A1 | |
| SCHEMBL3783593 | 0.72 | CYP3A4 (0.52) | HTTLMNATP53ADRB2MAPT | |
| SCHEMBL16676346 | 0.72 | HPGD (0.39) | HTTLMNATP53MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970176-B1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2023-10-25 | — | — | EP | disclosed |