Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26667471 | 1.00 | ALDH1A1 (0.44) | ALDH1A1HPGDDUSP3PTPN5PTPN11 | |
| SCHEMBL26667464 | 0.86 | AGTR1 (0.47) | ALDH1A1HPGDPOLBMEN1KMT2A | |
| SCHEMBL26667470 | 0.86 | AGTR1 (0.47) | ALDH1A1HPGDPOLBMEN1KMT2A | |
| SCHEMBL26902846 | 0.85 | FOLH1 (0.48) | ALDH1A1HPGDDUSP3PTPN5PTPN11 | |
| SCHEMBL30613477 | 0.85 | FOLH1 (0.48) | ALDH1A1HPGDDUSP3PTPN5PTPN11 | |
| SCHEMBL394112 | 0.81 | MEN1 (0.62) | ALDH1A1HPGDDUSP3PTPN5PTPN11 | |
| SCHEMBL394111 | 0.81 | MEN1 (0.62) | ALDH1A1HPGDDUSP3PTPN5PTPN11 | |
| SCHEMBL26667477 | 0.77 | ALDH1A1 (0.42) | ALDH1A1HPGDDUSP3PTPN5PTPN11 | |
| SCHEMBL26667481 | 0.77 | ALDH1A1 (0.42) | ALDH1A1HPGDDUSP3PTPN5PTPN11 | |
| SCHEMBL7061501 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HPGDDUSP3PTPN5PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381146-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND USE THEREOF | HELIOS HUAMING BIOPHARMA CO., LTD. (CN) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381146-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND USE THEREOF | SSB, BTK, PADI6 | ALDH1A1 1123/4885HPGD 2296/4885DUSP3 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.