Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 13/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.43 |
| ▸ | INCENP | Q9NQS7 | 4/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14454693 | 0.72 | MAOA (0.39) | MAOAMAOB | |
| SCHEMBL29482274 | 0.72 | MAOA (0.39) | MAOAMAOB | |
| SCHEMBL28039454 | 0.72 | SYK (0.77) | SYKAURKBINCENPABCB1HTR1A | |
| SCHEMBL9072004 | 0.71 | MAOA (0.51) | MAOAMAOBTUBB4ATUBBTUBA3C | |
| SCHEMBL2667043 | 0.70 | CXCL12 (0.60) | MAOAMAOBTUBB4ATUBBTUBA3C | |
| SCHEMBL2666990 | 0.68 | MAOA (0.50) | MAOAMAOBTUBB4ATUBBTUBA3C | |
| SCHEMBL6268223 | 0.67 | MAOA (0.57) | MAOAMAOB | |
| SCHEMBL4342702 | 0.65 | SYK (0.67) | SYKAURKBINCENPABCB1HTR1A | |
| SCHEMBL30853451 | 0.65 | SYK (0.67) | SYKAURKBINCENPABCB1HTR1A | |
| Ammonia Solution, Strong SCHEMBL4267568 | 0.64 | SYK (0.65) | SYKAURKBINCENPABCB1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007061923-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-05-31 | — | — | WO | disclosed |