Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667043 | 0.88 | CXCL12 (0.60) | MAOAMAOBTUBB4ATUBBTUBA3C | |
| SCHEMBL2666990 | 0.80 | MAOA (0.50) | MAOAMAOBTUBB4ATUBBTUBA3C | |
| SCHEMBL2666926 | 0.76 | MAOA (0.44) | MAOAMAOBCA1CA2HSP90AA1 | |
| SCHEMBL28137299 | 0.74 | CA1 (0.65) | MAOAMAOBTUBB4ATUBBTUBA3C | |
| SCHEMBL2666928 | 0.72 | HTR2C (0.41) | MAOAMAOBHSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL2666744 | 0.71 | KCNK9 (0.51) | MAOAMAOBTSHRALDH1A1MAPT | |
| SCHEMBL2666743 | 0.71 | PKM (0.41) | MAOAMAOBCA1CA2HSP90AA1 | |
| SCHEMBL2667068 | 0.71 | HTR2C (0.40) | MAOAMAOBHSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL1660314 | 0.71 | MAOA (0.61) | MAOAMAOBTUBB4ATUBBTUBA3C | |
| SCHEMBL2666940 | 0.71 | SYK (0.44) | MAOAMAOBTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007061923-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-05-31 | — | — | WO | disclosed |