Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708458 | 0.79 | RECQL (0.51) | RECQLKDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL3971478 | 0.79 | ALDH1A1 (0.46) | RECQLKDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL2433371 | 0.78 | RECQL (0.53) | RECQLKDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL31685547 | 0.78 | RECQL (0.53) | RECQLKDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL12143815 | 0.78 | DAO (0.41) | RECQLKDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL3580750 | 0.78 | RECQL (0.34) | RECQLKDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL6168942 | 0.78 | RECQL (0.53) | RECQLKDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL23222270 | 0.75 | KDM4E (0.51) | RECQLKDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL11900387 | 0.75 | LMNA (0.59) | RECQLKDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL10332862 | 0.73 | RECQL (0.49) | RECQLKDM4EPOLBSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486807-A | Antitumor fluorouracil and preparation process thereof | 海南卓科制药有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-117486807-A | Antitumor fluorouracil and preparation process thereof | 海南卓科制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | Asteroid Therapeutics | 2023-10-26 | — | — | US | disclosed |
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | Asteroid Therapeutics | 2023-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | SREBF1, SREBF2, NR1H3 | RECQL 3646/4885KDM4E 2203/4885POLB 4003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.