Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.33 |
| ▸ | DPYD | Q12882 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26669557 | 0.78 | RECQL (0.54) | RECQLHCAR2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL3971478 | 0.78 | ALDH1A1 (0.46) | RECQLHCAR2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL12143815 | 0.76 | DAO (0.41) | RECQLHCAR2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL28071084 | 0.74 | — | — | |
| SCHEMBL2640736 | 0.73 | RECQL (0.33) | RECQLHCAR2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL18770028 | 0.68 | — | — | |
| SCHEMBL16466339 | 0.68 | KDM6B (0.56) | DPYDLMNAPOLBHTTL3MBTL1 | |
| SCHEMBL7708458 | 0.67 | RECQL (0.51) | RECQLKDM4ELMNAPOLBHTT | |
| SCHEMBL25646153 | 0.67 | — | — | |
| SCHEMBL13187575 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466163-B2 | Furo[2,3-d]pyrimidines and related compounds and methods for treating disease states by inhibiting tubulin polymerization | BIONOMICS LIMITED (AU) | 2013-06-18 | — | — | US | disclosed |
| US-20100048591-A1 | CHEMICAL COMPOUNDS AND PROCESSES | BIONOMICS LIMITED (AU) | 2010-02-25 | — | — | US | disclosed |
| WO-2008070908-A1 | CHEMICAL COMPOUNDS AND PROCESSES | BIONOMICS LIMITED (AU) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008070908-A1 | CHEMICAL COMPOUNDS AND PROCESSES | BIONOMICS LIMITED (AU) | 2008-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048591-A1 | CHEMICAL COMPOUNDS AND PROCESSES | LTC4S, HNMT, SQLE | RECQL 3027/4885HCAR2 899/4885DPYD 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.