Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | GNG2 | P59768 | 1/20 | 0.33 |
| ▸ | GNB1 | P62873 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7175506 | 0.89 | GRIN2D (0.41) | NPC1RAB9AGRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL866128 | 0.84 | NPC1 (0.39) | NPC1RAB9AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL13092307 | 0.78 | P2RX7 (0.38) | NPC1RAB9AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL10158645 | 0.74 | GRIN2D (0.42) | NPC1RAB9AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL11492053 | 0.72 | TAAR1 (0.34) | NPC1RAB9AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL13332559 | 0.71 | HSD17B1 (0.51) | HSD17B1P2RX7ALDH1A1KMT2AMEN1 | |
| SCHEMBL11810833 | 0.71 | MEN1 (0.52) | HSD17B1KMT2ANPSR1MEN1 | |
| Benzylamine SCHEMBL15270988 | 0.70 | LOXL2 (0.48) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL10290603 | 0.70 | MAPT (0.48) | NPC1RAB9AHSD17B1GNG2GNB1 | |
| SCHEMBL11984545 | 0.69 | AR (0.33) | NPC1RAB9AP2RX7GNG2GNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4269415-A1 | TETRAHYDRO THIENOPYRIDINE SULFONAMIDE COMPOUND | Modulus Discovery, Inc. (JP) | 2023-11-01 | — | — | EP | disclosed |