Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667487 | 0.89 | MAPK1 (0.41) | RAB9ASMN1; SMN2NOX1KDM4ECASP3 | |
| SCHEMBL2667486 | 0.87 | GCK (0.44) | GCKNPC1RAB9AMAPTHPGD | |
| SCHEMBL2667826 | 0.87 | MAPK1 (0.55) | NPC1MAPTSMN1; SMN2POLBPKM | |
| SCHEMBL9070867 | 0.82 | SCD (0.56) | GCKNPC1RAB9AMAPTHPGD | |
| SCHEMBL2667671 | 0.80 | GRM5 (0.48) | GCKNPC1RAB9AMAPTHPGD | |
| SCHEMBL9070872 | 0.79 | NPC1 (0.56) | GCKNPC1RAB9AMAPTHPGD | |
| SCHEMBL9071034 | 0.78 | MAPT (0.52) | GCKNPC1RAB9AMAPTHPGD | |
| SCHEMBL9071035 | 0.78 | MAPT (0.52) | GCKNPC1RAB9AMAPTHPGD | |
| SCHEMBL9071036 | 0.78 | MAPT (0.52) | GCKNPC1RAB9AMAPTHPGD | |
| SCHEMBL9070810 | 0.78 | GCK (0.48) | GCKNPC1RAB9AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |