Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 2/20 | 0.41 |
| ▸ | CPT1A | P50416 | 8/20 | 0.40 |
| ▸ | CPT1B | Q92523 | 8/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667826 | 0.91 | MAPK1 (0.55) | MAPK1HTTLMNATSHRALDH1A1 | |
| SCHEMBL2667485 | 0.89 | GCK (0.45) | NOX1CASP3SENP8SENP6RAB9A | |
| SCHEMBL2667486 | 0.85 | GCK (0.44) | MAPK1NOX1CASP3SENP8SENP6 | |
| SCHEMBL2667686 | 0.81 | MAPK1 (0.43) | MAPK1HTTPDE5ACPT1ACPT1B | |
| SCHEMBL9070809 | 0.79 | MAPK1 (0.45) | MAPK1HTTPDE5ACPT1ACPT1B | |
| SCHEMBL9071068 | 0.79 | MEN1 (0.45) | MAPK1HTTCPT1ACPT1BSCD | |
| SCHEMBL2667666 | 0.79 | SCD (0.48) | PDE5ACPT1ACPT1BSCDLMNA | |
| SCHEMBL2667590 | 0.79 | MAPK1 (0.47) | MAPK1HTTPDE5ACPT1ACPT1B | |
| SCHEMBL2667659 | 0.79 | SCD (0.50) | MAPK1HTTPDE5ASCDALDH1A1 | |
| SCHEMBL2668009 | 0.78 | GRM5 (0.48) | MAPK1HTTPDE5ACPT1ACPT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |