Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 17/20 | 0.42 |
| ▸ | GIPR | P48546 | 9/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667850 | 0.89 | GCGR (0.40) | GCGRGIPRCYP3A4CYP2C9KCNH2 | |
| SCHEMBL13748622 | 0.87 | GCGR (0.47) | GCGRGIPRCYP3A4CYP2C9KCNH2 | |
| SCHEMBL2251290 | 0.83 | GCGR (0.45) | GCGRGIPRCYP3A4CYP2C9KCNH2 | |
| SCHEMBL2253028 | 0.81 | GCGR (0.62) | GCGRGIPRCYP3A4CYP2C9KCNH2 | |
| SCHEMBL2253932 | 0.79 | GCGR (0.48) | GCGRGIPRCYP3A4CYP2C9KCNH2 | |
| SCHEMBL2667403 | 0.79 | GCGR (0.64) | GCGRGIPR | |
| SCHEMBL13748634 | 0.75 | GCGR (0.46) | GCGRGIPRCYP3A4CYP2C9KCNH2 | |
| SCHEMBL2254697 | 0.74 | MAPT (0.47) | GCGRGIPR | |
| SCHEMBL2250997 | 0.72 | GCGR (0.45) | GCGRGIPRCYP3A4CYP2C9KCNH2 | |
| SCHEMBL13003086 | 0.72 | GCGR (0.43) | GCGRGIPRCYP3A4CYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069158-A2 | SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 2004-08-19 | — | — | WO | disclosed |