Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CPT1A | P50416 | 9/20 | 0.42 |
| ▸ | CPT1B | Q92523 | 9/20 | 0.42 |
| ▸ | GCK | P35557 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070943 | 0.93 | GCK (0.45) | ALDH1A1CPT1ACPT1BGCKMAPT | |
| SCHEMBL9070911 | 0.93 | GCK (0.46) | ALDH1A1CPT1ACPT1BGCKMAPT | |
| SCHEMBL9070840 | 0.92 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL2667481 | 0.92 | F2 (0.42) | CPT1ACPT1BGCKMAPTCYP1A2 | |
| SCHEMBL9070953 | 0.90 | SCD (0.46) | ALDH1A1CPT1ACPT1BGCKMAPT | |
| SCHEMBL9070839 | 0.89 | POLB (0.47) | ALDH1A1GCKMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL2667351 | 0.87 | GCK (0.48) | ALDH1A1GCKMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL2667766 | 0.85 | GCK (0.41) | ALDH1A1GCKMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL2667778 | 0.85 | GCK (0.49) | ALDH1A1GCKSMN1; SMN2SCDLMNA | |
| SCHEMBL9070969 | 0.85 | GCK (0.54) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |