Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 4/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | CPT1A | P50416 | 8/20 | 0.41 |
| ▸ | CPT1B | Q92523 | 8/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070911 | 0.98 | GCK (0.46) | GCKF2F10CPT1ACPT1B | |
| SCHEMBL2667481 | 0.94 | F2 (0.42) | GCKF2F10CPT1ACPT1B | |
| SCHEMBL2667552 | 0.93 | ALDH1A1 (0.43) | GCKCPT1ACPT1BALDH1A1LMNA | |
| SCHEMBL9070969 | 0.92 | GCK (0.54) | GCKKCNH2 | |
| SCHEMBL9070948 | 0.92 | MAPT (0.53) | GCKALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL2667766 | 0.91 | GCK (0.41) | GCKF2F10KCNH2ALDH1A1 | |
| SCHEMBL9070915 | 0.90 | MAPT (0.53) | GCKALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL2667694 | 0.90 | GCK (0.48) | GCKF2F10CPT1ACPT1B | |
| SCHEMBL9070833 | 0.88 | GCK (0.50) | GCKF2F10CPT1ACPT1B | |
| SCHEMBL2667474 | 0.86 | MAPT (0.51) | ALDH1A1LMNATSHRMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |