Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | AQP4 | P55087 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.39 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070866 | 0.88 | KDM4E (0.47) | GCKLMNAKDM4ERAB9ANOX1 | |
| SCHEMBL2664680 | 0.86 | GCK (0.64) | GCKLMNAKDM4EECE1CSNK2A2 | |
| SCHEMBL2667681 | 0.86 | GCK (0.50) | GCKKDM4ECSNK2A2CSNK2A1RAB9A | |
| SCHEMBL2667619 | 0.85 | NPC1 (0.51) | GCKRAB9AHPGD | |
| SCHEMBL2667707 | 0.84 | RAB9A (0.44) | GCKLMNAKDM4ERAB9AAQP4 | |
| SCHEMBL2667666 | 0.83 | SCD (0.48) | GCKLMNAKDM4EALDH1A1 | |
| SCHEMBL2667716 | 0.82 | KDM4E (0.48) | GCKLMNAKDM4ECSNK2A2CSNK2A1 | |
| SCHEMBL2667656 | 0.81 | KDM4E (0.43) | LMNAKDM4ERAB9A | |
| SCHEMBL9070891 | 0.81 | NOX1 (0.49) | GCKLMNAKDM4ERARARARB | |
| SCHEMBL9070883 | 0.81 | NOX1 (0.49) | GCKLMNAKDM4ERARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |