Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ESRRA | P11474 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.37 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070866 | 0.89 | KDM4E (0.47) | KDM4ERAB9ALMNAMEN1KMT2A | |
| SCHEMBL2667636 | 0.86 | RAB9A (0.52) | RAB9AMEN1NPC1KMT2A | |
| SCHEMBL2667637 | 0.86 | SCD (0.52) | RAB9AMEN1NPC1KMT2A | |
| SCHEMBL2667707 | 0.85 | RAB9A (0.44) | KDM4ERAB9ALMNAKCNH2CA12 | |
| SCHEMBL2667659 | 0.83 | SCD (0.50) | KDM4ERAB9APOLB | |
| SCHEMBL2667653 | 0.81 | GCK (0.49) | KDM4ERAB9ALMNA | |
| SCHEMBL2667716 | 0.80 | KDM4E (0.48) | KDM4ERAB9ALMNAPOLB | |
| SCHEMBL9070916 | 0.79 | ALDH1A1 (0.45) | KDM4ERAB9ALMNAKCNH2POLB | |
| SCHEMBL2667596 | 0.79 | RAB9A (0.49) | KDM4ERAB9ALMNACA12CA1 | |
| SCHEMBL9070874 | 0.78 | RAB9A (0.59) | KDM4ERAB9ALMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |