SCHEMBL26677698

SCHEMBL26677698

CCN1Cc2nn(C)nc2-c2cccc(N)c21

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TYK2 P29597 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25573062 0.83 TYK2 (0.37) TYK2
SCHEMBL29866564 0.83 TYK2 (0.37) TYK2
SCHEMBL27107334 0.82 DPP4 (0.32) TYK2
SCHEMBL26677547 0.79 GAA (0.36)
SCHEMBL29866220 0.78 TYK2 (0.38) TYK2
SCHEMBL29866375 0.76 TYK2 (0.44) TYK2
SCHEMBL29866515 0.75 MAPT (0.31) TYK2
SCHEMBL21539460 0.71 KDM4E (0.37)
SCHEMBL27107221 0.67 TYK2 (0.38) TYK2
SCHEMBL31274367 0.67 TYK2 (0.33) TYK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720064-A1 FUSED AZOLED AS TYK2 INHIBITORS AND USES THEREOF Sudo Biosciences Limited (GB) 2026-04-08 EP disclosed
EP-4532485-A1 TYK2 INHIBITORS AND USES THEREOF Sudo Biosciences Limited (GB) 2025-04-09 EP disclosed
WO-2024246602-A1 FUSED AZOLED AS TYK2 INHIBITORS AND USES THEREOF SUDO BIOSCIENCES LIMITED (GB) 2024-12-05 WO disclosed
WO-2023227946-A1 TYK2 INHIBITORS AND USES THEREOF SUDO BIOSCIENCES LIMITED (GB) 2023-11-30 WO disclosed
WO-2023227946-A1 TYK2 INHIBITORS AND USES THEREOF SUDO BIOSCIENCES LIMITED (GB) 2023-11-30 WO disclosed