Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GCK | P35557 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 9/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667602 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTGCKBRD4RAB9A | |
| SCHEMBL9070829 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTGCKBRD4RAB9A | |
| SCHEMBL2667944 | 0.82 | MAPT (0.52) | SMN1; SMN2MAPTGCKRAB9ANPC1 | |
| SCHEMBL9070805 | 0.82 | RAB9A (0.50) | SMN1; SMN2RAB9AMAPK1NPC1LMNA | |
| SCHEMBL2667721 | 0.82 | GCK (0.56) | SMN1; SMN2MAPTGCKBRD4RAB9A | |
| SCHEMBL9070865 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTGCKBRD4RAB9A | |
| SCHEMBL2667594 | 0.81 | GCK (0.49) | SMN1; SMN2MAPTGCKBRD4RAB9A | |
| SCHEMBL9070875 | 0.81 | GCK (0.56) | SMN1; SMN2MAPTGCKBRD4RAB9A | |
| SCHEMBL2667934 | 0.81 | GCK (0.62) | SMN1; SMN2MAPTGCKBRD4 | |
| SCHEMBL2667800 | 0.81 | RAB9A (0.55) | SMN1; SMN2MAPTGCKBRD4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |