Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | GCK | P35557 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.48 |
| ▸ | CCND3 | P30281 | 1/20 | 0.48 |
| ▸ | MAPK4 | P31152 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667602 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2BRD4MAPTGCKMAPK1 | |
| SCHEMBL9070865 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2BRD4MAPTGCKMAPK1 | |
| SCHEMBL2667721 | 0.84 | GCK (0.56) | SMN1; SMN2BRD4MAPTGCKMAPK1 | |
| SCHEMBL2667938 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2BRD4MAPTGCKMAPK1 | |
| SCHEMBL2667594 | 0.83 | GCK (0.49) | SMN1; SMN2BRD4MAPTGCKMAPK1 | |
| SCHEMBL2667934 | 0.83 | GCK (0.62) | SMN1; SMN2BRD4MAPTGCK | |
| SCHEMBL9070875 | 0.83 | GCK (0.56) | SMN1; SMN2BRD4MAPTGCKMAPK1 | |
| SCHEMBL9070880 | 0.82 | RAB9A (0.55) | SMN1; SMN2BRD4MAPTGCKMAPK1 | |
| SCHEMBL2667800 | 0.82 | RAB9A (0.55) | SMN1; SMN2BRD4MAPTGCKMAPK1 | |
| SCHEMBL2667586 | 0.82 | RAB9A (0.55) | SMN1; SMN2BRD4MAPTGCKMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |