Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GCK | P35557 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | AQP4 | P55087 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070970 | 0.90 | GCK (0.51) | RAB9AKDM4EGCKPTGESALOX5 | |
| SCHEMBL2667946 | 0.87 | SMN1; SMN2 (0.53) | RAB9AGCKPTGESALOX5SMN1; SMN2 | |
| SCHEMBL2667643 | 0.86 | RAB9A (0.49) | RAB9AKDM4EGCKPTGESALOX5 | |
| SCHEMBL9070869 | 0.83 | RAB9A (0.51) | RAB9AKDM4ESMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL2667756 | 0.82 | KCNH2 (0.40) | RAB9AKDM4EGCKPTGESALOX5 | |
| SCHEMBL9070900 | 0.81 | RAB9A (0.55) | RAB9AKDM4ESMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL2667947 | 0.81 | CASP3 (0.56) | RAB9AKDM4ESMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL9070892 | 0.80 | GCK (0.43) | RAB9AKDM4EGCKPTGESALOX5 | |
| SCHEMBL2664677 | 0.80 | GCK (0.66) | RAB9AKDM4EGCKL3MBTL1LMNA | |
| SCHEMBL2667940 | 0.79 | GCK (0.68) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |