Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GCK | P35557 | 2/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667716 | 0.81 | KDM4E (0.48) | HSD17B10LMNARAB9AKDM4EALDH1A1 | |
| SCHEMBL2667712 | 0.81 | NPC1 (0.53) | HTTTSHRNPC1RAB9AKDM4E | |
| SCHEMBL2668008 | 0.81 | NPC1 (0.51) | NPC1RAB9AMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL9070864 | 0.80 | NPC1 (0.54) | HTTNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL2667713 | 0.76 | NPC1 (0.52) | HTTTSHRNPC1RAB9AKDM4E | |
| SCHEMBL2667715 | 0.76 | NPC1 (0.50) | NPC1RAB9AMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL2667943 | 0.76 | NPC1 (0.54) | HTTTSHRHSD17B10LMNANPC1 | |
| SCHEMBL2667954 | 0.75 | GCK (0.76) | GCK | |
| SCHEMBL2667642 | 0.72 | KDM4E (0.48) | HSD17B10LMNARAB9AKDM4EALDH1A1 | |
| SCHEMBL9070866 | 0.72 | KDM4E (0.47) | TSHRHSD17B10LMNARAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |