Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070899 | 0.79 | RAB9A (0.49) | NPC1RAB9AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9070900 | 0.79 | RAB9A (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9070898 | 0.78 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL2667941 | 0.76 | NPC1 (0.57) | NPC1RAB9AHTTSMN1; SMN2TP53 | |
| SCHEMBL2667951 | 0.76 | HTT (0.47) | NPC1RAB9AHTTSMN1; SMN2TP53 | |
| SCHEMBL9070896 | 0.71 | HCAR3 (0.52) | — | |
| SCHEMBL6372226 | 0.68 | MAPT (0.71) | NPC1RAB9AHTTSMN1; SMN2TP53 | |
| SCHEMBL27800812 | 0.68 | RAF1 (0.51) | NPC1RAB9AHTTSMN1; SMN2TP53 | |
| SCHEMBL2667942 | 0.68 | RAB9A (0.62) | NPC1RAB9AHTTSMN1; SMN2TP53 | |
| SCHEMBL14999469 | 0.66 | SMN1; SMN2 (0.74) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |