Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070893 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9ANPC1LMNAMETAP2 | |
| SCHEMBL2667946 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2BRD4MAPTRAB9ANPC1 | |
| SCHEMBL2667605 | 0.85 | NPC1 (0.48) | SMN1; SMN2BRD4MAPTRAB9ANPC1 | |
| SCHEMBL2667755 | 0.84 | NPC1 (0.46) | SMN1; SMN2RAB9ANPC1LMNAMETAP2 | |
| SCHEMBL2667624 | 0.83 | RAB9A (0.46) | SMN1; SMN2BRD4MAPTRAB9ANPC1 | |
| SCHEMBL2667608 | 0.80 | GCK (0.60) | — | |
| SCHEMBL9070795 | 0.76 | GCK (0.47) | SMN1; SMN2BRD4MAPTRAB9ANPC1 | |
| SCHEMBL9070971 | 0.76 | GCK (0.53) | SMN1; SMN2BRD4MAPTRAB9ANPC1 | |
| SCHEMBL9070892 | 0.75 | GCK (0.43) | SMN1; SMN2MAPTRAB9ANPC1LMNA | |
| SCHEMBL2667945 | 0.74 | RAB9A (0.51) | SMN1; SMN2BRD4MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |