Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801239 | 0.88 | ALDH2 (0.41) | SIGMAR1ABCB1MAOBALDH2MAOA | |
| SCHEMBL29180250 | 0.78 | MAOB (0.43) | ABCB1MAOBALDH2MAOAABCG2 | |
| SCHEMBL26676629 | 0.78 | ABCB1 (0.44) | SIGMAR1ABCB1ABCC1ABCG2 | |
| SCHEMBL21801231 | 0.78 | MAOB (0.43) | ABCB1MAOBALDH2MAOAABCG2 | |
| SCHEMBL21801087 | 0.77 | CYSLTR1 (0.43) | SIGMAR1ABCB1MAOBALDH2MAOA | |
| SCHEMBL21801088 | 0.77 | CYSLTR1 (0.43) | SIGMAR1ABCB1MAOBALDH2MAOA | |
| SCHEMBL30744086 | 0.77 | ALDH2 (0.41) | SIGMAR1ABCB1MAOBALDH2MAOA | |
| SCHEMBL21801085 | 0.77 | ALDH2 (0.41) | SIGMAR1ABCB1MAOBALDH2MAOA | |
| SCHEMBL21865652 | 0.77 | MAOB (0.38) | SIGMAR1ABCB1MAOBMAOAABCC1 | |
| SCHEMBL21865770 | 0.76 | TERT (0.33) | TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3849966-B1 | FLAVONE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE | HOFFMANN LA ROCHE (CH) | 2023-10-25 | — | — | EP | disclosed |