Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 7/20 | 0.37 |
| ▸ | BCHE | P06276 | 5/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21865650 | 0.86 | MAOB (0.38) | MAOBCSNK2A2CSNK2BCSNK2A1ACHE | |
| SCHEMBL21801226 | 0.86 | MAOB (0.41) | MAOBCSNK2A2CSNK2BCSNK2A1ACHE | |
| SCHEMBL21801077 | 0.85 | ABCB1 (0.38) | MAOBCSNK2A2CSNK2BCSNK2A1BCHE | |
| SCHEMBL26680673 | 0.77 | SIGMAR1 (0.38) | MAOBABCB1ABCC1ABCG2MAOA | |
| SCHEMBL26680095 | 0.75 | MAOB (0.41) | MAOBCSNK2A2CSNK2BCSNK2A1ACHE | |
| SCHEMBL21801229 | 0.74 | MAOB (0.42) | MAOBCSNK2A2CSNK2BCSNK2A1BCHE | |
| SCHEMBL21801126 | 0.74 | MAOB (0.42) | MAOBCSNK2A2CSNK2BCSNK2A1BCHE | |
| SCHEMBL30744121 | 0.74 | MAOB (0.42) | MAOBCSNK2A2CSNK2BCSNK2A1BCHE | |
| SCHEMBL21801244 | 0.73 | ABCG2 (0.42) | MAOBABCB1ABCC1ABCG2MAOA | |
| SCHEMBL21886453 | 0.72 | ABCG2 (0.41) | MAOBBCHEABCB1ABCC1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3849966-B1 | FLAVONE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE | HOFFMANN LA ROCHE (CH) | 2023-10-25 | — | — | EP | disclosed |
| WO-2020053249-A1 | FLAVONE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2020-03-19 | — | — | WO | disclosed |