Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26683140 | 0.81 | CYP11B1 (0.39) | CYP11B1CYP11B2ERN1HSD17B1CHRNB2 | |
| SCHEMBL30687719 | 0.81 | CYP11B1 (0.39) | CYP11B1CYP11B2ERN1HSD17B1CHRNB2 | |
| SCHEMBL26683191 | 0.80 | RXRA (0.46) | ALDH1A3ERN1HSD17B1 | |
| SCHEMBL26682888 | 0.78 | PIP4K2A (0.38) | CYP11B1CYP11B2ERN1HSD17B1CYP1A1 | |
| SCHEMBL1748564 | 0.77 | ALDH1A3 (0.55) | ALDH1A3ERN1CYP1A1CYP1B1PTGS2 | |
| SCHEMBL18002608 | 0.74 | ALDH1A3 (0.51) | ALDH1A3ERN1 | |
| SCHEMBL1121444 | 0.74 | ALDH1A3 (0.63) | ALDH1A3ERN1CHRNB2CHRNA4CYP1A1 | |
| SCHEMBL12037831 | 0.74 | ALDH1A3 (0.63) | ALDH1A3ERN1CHRNB2CHRNA4 | |
| SCHEMBL17820413 | 0.73 | CHRNB2 (0.54) | ALDH1A3CYP11B1CYP11B2FDPSERN1 | |
| SCHEMBL26681988 | 0.70 | ERN1 (0.36) | CYP11B1CYP11B2ERN1HSD17B1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4279476-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-22 | — | — | EP | disclosed |