Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.44 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.43 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26680654 | 0.94 | CHRM3 (0.52) | CHRM3LMNAPRKD1CHRNA10CHRNA9 | |
| SCHEMBL30687630 | 0.90 | TP53 (0.44) | CHRM3LMNAPRKD1CHRNA10CHRNA9 | |
| SCHEMBL26681019 | 0.90 | TP53 (0.44) | CHRM3LMNAPRKD1CHRNA10CHRNA9 | |
| SCHEMBL30687743 | 0.89 | CHRM3 (0.46) | CHRM3PRKD1CHRNA10CHRNA9DRD4 | |
| SCHEMBL26682995 | 0.89 | CHRM3 (0.46) | CHRM3PRKD1CHRNA10CHRNA9DRD4 | |
| SCHEMBL26680977 | 0.88 | CHRNA10 (0.41) | CHRM3CHRNA10CHRNA9DRD4MAPT | |
| SCHEMBL26681259 | 0.88 | CHRM3 (0.48) | CHRM3LMNAPRKD1DRD4MAPT | |
| SCHEMBL30687773 | 0.88 | RXRA (0.49) | CHRM3LMNADRD4MAPTDRD2 | |
| SCHEMBL26680482 | 0.88 | RXRA (0.49) | CHRM3LMNADRD4MAPTDRD2 | |
| SCHEMBL26682507 | 0.88 | ALDH1A1 (0.42) | CHRM3LMNAMAPTKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4279476-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-22 | — | — | EP | disclosed |