Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.42 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.41 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 4/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26681019 | 1.00 | TP53 (0.44) | TP53POLBMAPTHSD17B10KDM4E | |
| SCHEMBL26681259 | 0.91 | CHRM3 (0.48) | TP53POLBMAPTHSD17B10KDM4E | |
| SCHEMBL26683056 | 0.90 | CHRM3 (0.46) | TP53MAPTHSD17B10KDM4ETSHR | |
| SCHEMBL26682606 | 0.89 | TP53 (0.43) | TP53POLBMAPTL3MBTL1CHRNA10 | |
| SCHEMBL30687743 | 0.88 | CHRM3 (0.46) | TP53MAPTHSD17B10KDM4ETSHR | |
| SCHEMBL26682995 | 0.88 | CHRM3 (0.46) | TP53MAPTHSD17B10KDM4ETSHR | |
| SCHEMBL26682099 | 0.87 | RXRA (0.49) | TP53MAPTHSD17B10KDM4ETSHR | |
| SCHEMBL26681987 | 0.87 | P2RX7 (0.39) | TP53POLBMAPTHSD17B10KDM4E | |
| SCHEMBL26682632 | 0.87 | BCL2 (0.47) | TP53POLBMAPTHSD17B10KDM4E | |
| SCHEMBL26681374 | 0.85 | MAPT (0.63) | TP53MAPTHSD17B10KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4279476-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-22 | — | — | EP | disclosed |