Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | KRAS | P01116 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.35 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 3/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30632448 | 1.00 | OXTR (0.38) | OXTRAVPR1AKRASEGLN2RORC | |
| SCHEMBL30632526 | 0.86 | SMARCA2 (0.50) | OXTRAVPR1AKRASEGLN2RORC | |
| SCHEMBL26685126 | 0.86 | SMARCA2 (0.50) | OXTRAVPR1AKRASEGLN2RORC | |
| SCHEMBL26685199 | 0.83 | OXTR (0.34) | OXTRAVPR1AKRASEGLN2RORC | |
| SCHEMBL30632439 | 0.83 | OXTR (0.34) | OXTRAVPR1AKRASEGLN2RORC | |
| SCHEMBL26685440 | 0.71 | EGLN2 (0.42) | OXTRAVPR1AKRASEGLN2RORC | |
| SCHEMBL30632460 | 0.71 | EGLN2 (0.42) | OXTRAVPR1AKRASEGLN2RORC | |
| SCHEMBL31293862 | 0.71 | OXTR (0.40) | OXTRAVPR1AKRASEGLN2CYP11B2 | |
| SCHEMBL31570177 | 0.71 | SMYD3 (0.31) | — | |
| SCHEMBL31293622 | 0.68 | SMARCA2 (0.53) | OXTRAVPR1AKRASEGLN2CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220129-A1 | BENZOYPARAZINE PYRAZINES ANE THEIR USES | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |