Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 4/20 | 0.50 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.50 |
| ▸ | PBRM1 | Q86U86 | 4/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26685126 | 1.00 | SMARCA2 (0.50) | SMARCA2SMARCA4PBRM1CYP11B2OXTR | |
| SCHEMBL30632448 | 0.86 | OXTR (0.38) | SMARCA2SMARCA4PBRM1CYP11B2OXTR | |
| SCHEMBL26685133 | 0.86 | OXTR (0.38) | SMARCA2SMARCA4PBRM1CYP11B2OXTR | |
| SCHEMBL31293622 | 0.82 | SMARCA2 (0.53) | SMARCA2SMARCA4PBRM1CYP11B2OXTR | |
| SCHEMBL26684891 | 0.80 | PBRM1 (0.39) | SMARCA2SMARCA4PBRM1NR1I2 | |
| SCHEMBL31570161 | 0.80 | PBRM1 (0.39) | SMARCA2SMARCA4PBRM1NR1I2 | |
| SCHEMBL30632439 | 0.79 | OXTR (0.34) | CYP11B2OXTRAVPR1APARP1GPR119 | |
| SCHEMBL26685199 | 0.79 | OXTR (0.34) | CYP11B2OXTRAVPR1APARP1GPR119 | |
| SCHEMBL30632451 | 0.79 | SMARCA2 (0.43) | SMARCA2SMARCA4PBRM1CYP11B2PARP1 | |
| SCHEMBL26685144 | 0.79 | SMARCA2 (0.43) | SMARCA2SMARCA4PBRM1CYP11B2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119998278-A | Compounds and uses thereof | 福宏治疗公司 | 2025-05-13 | — | — | CN | disclosed |
| EP-4522278-A1 | BENZOYPARAZINE PYRAZINES ANE THEIR USES | Foghorn Therapeutics Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220129-A1 | BENZOYPARAZINE PYRAZINES ANE THEIR USES | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |