Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2668561 | 0.85 | PIK3CD (0.38) | PIK3CDALOX5TP53 | |
| SCHEMBL8300064 | 0.84 | PIK3CD (0.50) | PIK3CDALOX5 | |
| SCHEMBL8030775 | 0.83 | PIK3CD (0.39) | PIK3CD | |
| SCHEMBL13351518 | 0.81 | ALDH1A1 (0.41) | PIK3CD | |
| SCHEMBL27971919 | 0.80 | ADH1A (0.47) | ALOX5 | |
| Hydrochloric Acid SCHEMBL27529969 | 0.79 | ADH1A (0.46) | ALOX5 | |
| SCHEMBL21197527 | 0.79 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL12204020 | 0.79 | MEN1 (0.35) | PIK3CDALOX5TP53 | |
| SCHEMBL2497168 | 0.78 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL30296278 | 0.78 | ALOX5 (0.41) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2377856-A1 | Urea glucokinase activators | NOVO NORDISK A/S (DK) | 2011-10-19 | — | — | EP | disclosed |
| WO-2007006814-A1 | UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |