⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31568028 | 0.75 | PKLR (0.33) | — | |
| SCHEMBL31568035 | 0.75 | TYK2 (0.42) | — | |
| SCHEMBL31543237 | 0.73 | OPRL1 (0.33) | — | |
| SCHEMBL31543238 | 0.72 | OPRL1 (0.33) | — | |
| SCHEMBL26877934 | 0.72 | OPRL1 (0.33) | — | |
| SCHEMBL26685551 | 0.72 | — | — | |
| SCHEMBL12475153 | 0.70 | BACE1 (0.36) | — | |
| SCHEMBL1598567 | 0.68 | MAP3K12 (0.40) | — | |
| SCHEMBL26685083 | 0.66 | PIK3CD (0.32) | — | |
| SCHEMBL16416755 | 0.64 | MAPT (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | BIOGEN MA INC. | 2025-10-02 | — | — | US | disclosed |
| EP-4522612-A1 | TYK2 INHIBITORS | Biogen MA Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| CN-119654322-A | TYK2 inhibitors | 渤健马萨诸塞州股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| WO-2023220046-A1 | TYK2 INHIBITORS | BIOGEN MA INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220046-A1 | TYK2 INHIBITORS | BIOGEN MA INC. (US) | 2023-11-16 | — | — | WO | disclosed |